Description
Dark Spot & Pigmentation Corrector 30g
Nanoskin Dark Spot and Pigmentation corrector delivers rapid results to even out skin tone and reveals a brighter more glowing skin in record time. You were born to sparkle. Correct sun damage and restore youthful looks. Be who you are. A sunny glowing person who brings joy to the world.
Rapid Dark Spot Pigmentation Correction and Skin Lightening
BACKGROUND
Pigmentation and uneven skin tone is a problem over a vast spectrum of skin colour and ethnic background within the human race. The application of topical ointments, creams, soaps and even household chemicals has become a modern trend to de-pigment and modulate the skin complex to fit in with society’s perceived demands. Many of these practices and chemicals are hazardous and can result in dermatological consequences some including; skin lesion, thinning of the skin, worse tissue discolouration (pigmentation), skin inflammation and ultimately resulting in permanent skin damage.
Pigmentation and the main determinant of skin colour is melanin. Melanocytes, pigment cells, are dendritic cells which is situated in the basal layer of the epidermis, producing the protein melanin. The amount of melanin product differs from human to human and in between ethnic groups. The production of melanin is a natural protection mechanism, protecting the skin against injury, and is influenced by factors like sun exposure, hormonal changes, medication use, genetic conditions and skin inflammation.
Skin colour is classified according to ethnic background and can be identified by using the Fitzpatrick types I-VI. Pigmentation disorders are often more troublesome in some Fitzpatrick types than in other. Pigmentation include freckles, liver spots/age spots, birthmarks, melasma and post-inflammatory hyper-pigmentation.
The need and demand for safer and effective de-pigmentation or anti-pigmentation products to even out the skin tone in all ethnic groups are undeniable important and cannot be overlooked. This global need has motivated Skin Scripts in collaboration with DRA Pharmaceuticals to develop a new and approved even tone moisturizer using the newest and approved active compounds. This product is formulated to even out any skin tone Fitzpatrick type I-VI in a more effective and safer manner.
During this prospective phase I study, the therapeutic efficacy and safety of an anti-pigmentation preparation will be evaluated, base on instrumental and observational assessment. Each participant will be his/her own control comparing initial photos of each participant to his/her own photos during the course of the trial. Data will be collected to supports claims to the effect of even skin appearance, removes ages spots and melasma and giving more homogeneous colour distribution in Fitzpatrick types I-VI.
PHARMACOLOGY
Visiblan (Octadecenedioic acid) is high-tolerance skincare active for a brighter and more even tone complexion. This is achieved by the regulation of genetic pigmentation and controlling the melanin pathway through the skin. The product is obtained by an eco-designed process from non-genetically modified organisms (GMO) sunflower seeds. Visiblan is of high purity and without toxicity on cells, unlike hydroquinone.
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Lumisphere
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Lumisphere™ is an instant and gradual skin brightener. It is an association of manganese titanium dioxide (TiO2Mn) that provides the skin with an instant even, luminous and mat complexion with no white residue, and Diacetyl Boldine (DAB) that brings a physiological lightening effect. TiO2Mn absorbs UVA & UVB and neutralises free radicals. DAB helps decrease the amount of melanin in the skin by stabilising tyrosinase in its inactive form.
MSM is an organo-sulfur compound, the sulphur content of MSM can be used to maintain normal connective tissue it also has, anti-inflammatory properties. MSM makes skin cells permeable and will increase the cellular concentration of all the other ingredients in the formulation.
Allantoin is naturally occurring compound and is keratolytic and keratoplastic. It has moisturizing, soothing and healing properties and is an anti-irritant and non-toxic agent. Allantoin enhances the desquamation of upper layers of dead skin cells and stimulate epidermal renewal process without any adverse effects. It provides a number of functions optimal for reducing the severity of an outbreak in the skin and promotes healing.
Niacinamide, an amide of vitamin B3, is a hydrophilic endogenous substance. It is anti-inflammatory by inhibition of 3′,5′-cyclic adenosine monophosphate (CAMP) phosphodiesterase. The ability to block the inflammatory actions is therefore important for the expression of adhesion molecules and pro-inflammatory mediators in acne. The anti-pigmentation effect of Niacinamide is mediated through the reversible blocking of the transfer of melanosomes from melanocytes into keratinocytes, by inhibiting keratinocyte factors.
